As part of the background to her process, Karle took 3D scan data of bones from the California Academy of Science’s collection and then rendered the data and applied generative algorithms to create sculptures. She also created sculptures growing crystals on 3D printed lattices. This work led her to pursue growing designs in actual bone with actual stem cells.
Regenerative Reliquary is a 3D printed scaffold made of biodegradable hydrogel that disintegrates over time, with the aim that stem cells seeded onto the design will grow tissue and mineralize into bone along the scaffold. To create this work, Karle collaborated with bio/nano and materials scientists at Autodesk. The project is still under development and Karle is seeking scientific and biomedical partners to collaborate on cell culture and establish repeatable successful results for stem cell grown into bone in this or a similar method. She is also seeking sponsors and museums to show this work.
Regenerative Reliquary: Bringing Bones To Life, Materia